Articular cartilage: amphoteric nature and interfacial energy
نویسندگان
چکیده
منابع مشابه
Biochemistry of articular cartilage. Nature of proteoglycans and collagen of articular cartilage and their role in ageing and in osteoarthrosis.
The cartilage which covers the articular surfaces of bones of vertebrate animals has two main functions: the limitation of stress applied to the bone extremities and the provision of the smooth surfaces necessary for the joint to function as an efficient bearing (Kempson, Spivey, Freeman, and Swanson, 1969). To meet these functional demands the cartilage exhibits a combination of physical prope...
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
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protein-chondroitin sulfate bonds.8 No similar mammalian enzymes in joint tissues were found until Ziff, et al.' demonstrated an agent extracted from the synovial membrane in cases of acute rheumatoid arthritis and related this to its content of granulocytes. Since this type of inflammation is not usually seen in osteoarthritis, it is of considerable interest that Lack' has suggested blood plas...
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A strain energy function for finite deformations is developed that has the capability to describe the nonlinear, anisotropic, and asymmetric mechanical response that is typical of articular cartilage. In particular, the bimodular feature is employed by including strain energy terms that are only mechanically active when the corresponding fiber directions are in tension. Furthermore, the strain ...
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important functions: joint lubrication, stress distribution to subchondral bone to minimize peak stress, and provision of a smooth low-friction surface. Repetitive and acute impact, as well as torsional joint loading can damage articular cartilage surfaces of the knee joint. Injury to articular cartilage can lead to pain, swelling, joint dysfunction, and possibly progressive joint degeneration....
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ژورنال
عنوان ژورنال: Journal of Clinical and Molecular Medicine
سال: 2018
ISSN: 2516-5593
DOI: 10.15761/jcmm.1000114